CD123

Interleukin-3 receptor - Wikipedia

The interleukin-3 receptor (CD123) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune ...

cd123

CD123 as a Therapeutic Target in the Treatment of Hematological ...

1. Cancers (Basel). 2019 Sep 12;11(9). pii: E1358. doi: 10.3390/ cancers11091358. CD123 as a Therapeutic Target in the Treatment of Hematological ...

cd123

CD 123 is a membrane biomarker and a therapeutic target in ...

10 Feb 2014 ... Given the low/absent CD123 expression on normal hematopoietic stem cells, attempts have been made at preclinical first, and then at clinical ...

cd123

Dual Expression of TCF4 and CD123 Is Highly Sensitive and ...

Dual Expression of TCF4 and CD123 Is Highly Sensitive and Specific For Blastic Plasmacytoid Dendritic Cell Neoplasm. Sukswai N(1)(2), Aung PP(3), Yin ...

cd123

CD123 Is a Useful Marker for Prediction of Clinical Outcome and ...

10 Jan 2019 ... CD123 (interleukin-3 receptor α chain) is highly expressed on leukemic stem cells but not on normal hematopoietic cells; therefore, it may ...

cd123

APC anti-human CD123 Antibody anti-CD123 - 6H6

CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β ...

cd123

Distribution and levels of cell surface expression of CD33 and ...

13 Jun 2014 ... Here, CD33 and CD123 expression on AML blasts was studied by flow cytometry in a cohort of 319 patients with detailed information on ...

cd123

Interleukin-3 receptor alpha chain (CD123) is widely expressed in ...

We analyzed the CD123 expression pattern in 64 patients with acute leukemia, 45 with acute myeloid leukemia (AML) and 19 with acute lymphocytic leukemia (  ...

cd123

Use of CD 123 Expression on Blasts from AML, ALL and RAEB As ...

3 Dec 2019 ... However, CD123 expression on blast cells and its prognostic value in different hematologic malignancies as acute myeloid leukemia (AML), ...

cd123

What is the meaning of CD123 expression by phenotypically normal ...

We observe CD123 positivity with certain frequency in granulocytes of patients with MDS or even in monocytes, although less frequently. We are not talking ...

cd123

IL3RA Gene - GeneCards | IL3RA Protein | IL3RA Antibody

... Interleukin 3 Receptor, Alpha (Low Affinity); Interleukin-3 Receptor Subunit Alpha; IL-3 Receptor Subunit Alpha; IL-3R Subunit Alpha; CD123 Antigen; IL-3R-  ...

cd123

APC - anti human CD123 - Clone AC145

CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, and megakaryocytes. At the level of the hematopoietic system ...

cd123

Dual CD19 and CD123 targeting prevents antigen-loss ... - JCI

29 Aug 2019 ... The IL-3 receptor α chain (CD123) is expressed in several hematologic neoplasms, including acute myeloid leukemia (AML), plasmacytoid ...

cd123

CD123 - Clinical: CD123 Immunostain, Technical Component Only

CD123 : In normal lymphoid tissues, CD123 is expressed in plasmacytoid monocytes and mast cells in interfollicular regions. In bone marrow, it is expressed in ...

cd123

CD123 antibodies, human - Primary antibodies - Antibodies - MACS ...

CD123 is also known as interleukin 3 (IL-3) receptor α-chain and is the primary low-affinity subunit of the IL-3 receptor. CD123 associates with CD131, the ...

cd123

Anti-Hu CD123 Pacific Blue™ - EXBIO Antibodies

The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein ...

cd123

Recombinant Human IL-3R alpha/CD123 Protein 301-R3-025: R&D ...

Measured by its binding ability in a functional ELISA. When Recombinant Human IL‑3 R alpha /CD123 is present at 1 μg/mL, the concentration of Recombinant ...

cd123

CD123 Antibody (14-1239-82)

Invitrogen Anti-CD123 Monoclonal (6H6), eBioscience™, Catalog # 14-1239-82. Tested in Immunohistochemistry (Frozen) (IHC (F)), Immunohistochemistry ...

cd123

CD123 expression levels in 846 acute leukemia patients based on ...

18 Nov 2019 ... Background: While it is known that CD123 is normally strongly expressed on plasmacytoid dendritic cells and completely absent on nucleated ...

cd123

Diagnostic and Prognostic Value of CD123 in Acute Myeloid ...

1 Sep 2019 ... Patients and Methods. The percentage of CD123 (+) cells in the blast population was determined at diagnosis using flowcytometry; expression > ...

cd123

CD123 (6H6) Mouse Monoclonal Antibody

CD123 monoclonal antibody stains a cytoplasmic/membranous pattern for blastic plasmacytoid dendritic cell neoplasm.

cd123

Anti-Human CD123 (IL-3Ra) Antibody, Clone 6H6

The anti-human CD123 clone 6H6 antibody reacts CD123 (IL-3 receptor subunit a) and has been verified for purity assessment of isolated cells.

cd123

FDA Grants Orphan Drug Designation to CD123-Targeted CAR T ...

24 Jul 2019 ... The FDA has granted an orphan drug designation to MB-102, a CD123-directed CAR T-cell therapy, for the treatment of patients with acute ...

cd123

Development of a new anti‐CD123 monoclonal antibody to target ...

4 Jul 2019 ... Development of a new anti‐CD123 monoclonal antibody to target the human CD123 antigen as an acute myeloid leukemia cancer stem cell ...

cd123

Consumables | Anti-Human CD123/IL-3R (6H6)-143Nd ... - Fluidigm

CD123 is the transmembrane α chain of the interleukin-3 (IL-3) receptor.

cd123

Abstract 1785: Pre-clinical development of a novel CD3-CD123 ...

1 Jul 2019 ... Abstract 1785: Pre-clinical development of a novel CD3-CD123 bispecific T-cell engager using Cross-Over-Dual-Variable-Domain (CODV) ...

cd123

Dose Escalation Study of JNJ-63709178, a Humanized CD123 x ...

22 Mar 2019 ... Dose Escalation Study of JNJ-63709178, a Humanized CD123 x CD3 DuoBody in Participants With Relapsed or Refractory Acute Myeloid ...

cd123

B14808, CD123-PE Conjugated Antibody, 9F5, 1 mL, ASR ...

Results 1 - 10 of 10 ... The CD123 antigen, alias Interleukin-3 alpha receptor (IL-3Rα), belongs to the cytokine receptor family. It is constitutively expressed by ...

cd123

Anti-IL3RA/CD123 antibody [6H6] (ab21562) | Abcam

Mouse monoclonal IL3RA/CD123 antibody [6H6]. Validated in WB, IP, IHC, Flow Cyt, ICC/IF and tested in Human. Cited in 1 publication(s). Independently ...

cd123

CD123 | NeoGenomics Laboratories

CD123 labels plasmacytoid dendritic cells and is useful in diagnosing neoplasms derived from these cells as well as reactive conditions, such as histiocytic ...

cd123

Cellectis death casts more doubt on CD123 | Evaluate

5 Sep 2019 ... Safety worries around targeting CD123 will only intensify with news of a patient death with Cellectis's off-the-shelf CAR-T therapy UCART123.

cd123

BD FastImmune™ CD63/CD123/Anti-HLA-DR

BD FastImmune™. CD63/CD123/Anti–HLA-DR. Catalog No. 341068. 50 Tests. 20 µL/test. RESEARCH. APPLICATIONS. Research applications include studies  ...

cd123

Anti-CD123 Antibody Products | Biocompare

558 products ... CD123 is a reported alias name for the human gene IL3RA, or 'interleukin 3 receptor subunit alpha'. The 378-amino acid protein is a member of the ...

cd123

CD123 antibody | antibody review based on formal publications

31 Jul 2019 ... CD123 synonym: CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra; interleukin-3 receptor subunit alpha; CD123 antigen; IL-3 receptor alpha SP2 ...

cd123

Characterization of SGN-CD123A, A Potent CD123-Directed ...

1 Feb 2019 ... Characterization of SGN-CD123A, A Potent CD123-Directed Antibody–Drug Conjugate for Acute Myeloid Leukemia. Fu Li, May Kung Sutherland, ...

cd123

Balance of Anti-CD123 Chimeric Antigen Receptor Binding Affinity ...

12 Apr 2019 ... good therapeutic target antigen. Overall, full dissection of these variables offers suitable anti-CD123 CAR design optimization for the treatment of ...

cd123

Human IL-3 R alpha / CD123 Protein, Llama IgG2b Fc Tag, low ...

IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, CD123, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha. Source. Human IL-3 R alpha , ...

cd123

Daunorubicin-Loaded CdTe QDs Conjugated with Anti-CD123 ...

24 Jan 2020 ... Daunorubicin-Loaded CdTe QDs Conjugated with Anti-CD123 mAbs: A Novel Delivery System for Myelodysplastic Syndromes Treatment.

cd123

CD123 - IHC Primary Antibodies

CD123 forms a heterodimer with CD131 (the beta subunit of the interleukin-3 receptor) to form the interleukin-3 receptor, where the cytokine specificity is provided ...

cd123

The expression of CD123 can decrease with basophil activation ...

1 Apr 2019 ... One of the commonly used is the combination of CD123 and HLA-DR [1, 2]. CD123 is the low affinity subunit of the IL-3 receptor and is highly ...

cd123

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